News & Media



Spinach and Fluorophore Publications

Diglycyl-Lysine Antibody Publications



The Scientist magazine compared and contrasted SpinachTM against the latest methods in tracking RNA in living cells.

Media coverage on the SpinachTM technology by BioTechniquesScience Daily, Popular Science, and GEN.

A poster titled "SpinachTM Splice Sensor: A Fluorescent Drug Screening Platform" was presented at the 2018 Society of Laboratory Automation and Screening conference.



Publications on SpinachTM and DFHBI Fluorophores:

Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria.  Nature Protocols.  January 9, 2014.  LINK

Plug-and-play fluorophores extend the spectral properties of Spinach.  Journal of the American Chemical Society.  January 6, 2014.  LINK

Understanding the Photophysics of the Spinach-DFHBI RNA Aptamer-Fluorogen Complex To Improve Live-Cell RNA Imaging.  Journal of the American Chemical Society.  December 18, 2013.  LINK

E88, a new cyclic-di-GMP class I riboswitch aptamer from Clostridium tetani, has a similar fold to the prototypical class I riboswitch, Vc2, but differentially binds to c-di-GMP analogs.  Molecular BioSystems.  December 18, 2013.  LINK

Gene position more strongly influences cell-free protein expression from operons than T7 transcriptional promoter strength.  ACS Synthetic Biology.  November 27, 2013.  LINK

A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA.  Nature Mehtods.  October 27, 2013.  LINK

Unbiased Tracking of the Progression of mRNA and Protein Synthesis in Bulk and in Liposome-Confined Reactions.  ChemBioChem.  September 11, 2013.  LINK

Universal aptamer-based real-time monitoring of enzymatic RNA synthesis.  Journal of the American Chemical Society.  September 18, 2013.  LINK

Programmable folding of fusion RNA in vivoand in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor.  Nucleic Acids Research.  September 9, 2013.  LINK

The Spinach RNA Aptamer as a Characterization Tool for Synthetic Biology.  ACS Synthetic Biology.  August 30, 2013.  LINK

New approaches for sensing metabolites and proteins in live cells using RNA.  Current Opinion in Chemical Biology.  August, 2013.  LINK

Imaging bacterial protein expression using genetically encoded RNA sensors.  Nature Methods.  July 21, 2013.  LINK

Designer nucleic acids to probe and program the cell.  Trends in Cell Biology.  December, 2012.  LINK

Nanomolar fluorescent detection of c-di-GMP using a modular aptamer strategy.  Chemical Communications.  July 20, 2012.  LINK

Fluorescence imaging of cellular metabolites with RNA.  Science.  March 9, 2012.  LINK

RNA mimics of green fluorescent protein.  Science.  July 29, 2011.  LINK



Publications on Diglycyl-Lysine Antibodies:

Comprehensive profiling of protein ubiquitination for drug discovery.  Current Pharmaceutical Design.  2013.  LINK

A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition.  Journal of Biology Chemistry.  October 11, 2013.   LINK

The new landscape of protein ubiquitination.  Nature  Biotechnology.  December 8, 2011.  LINK

Global identification of modular Cullin-RING ligase substrates.  Cell.  October 14, 2011.  LINK

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.  Molecular & Cellular Proteomics.  October 1, 2011.  LINK

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.  Nature Cell Biology.  September 23, 2012.  LINK

Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.  Molecular & Cellular Proteomics.  July 11, 2012.  LINK

Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling.  Nature  Biotechnology.  August 2010.  LINK