Spinach™ is a family of light-up RNA aptamers specifically designed to activate a series of fluorogenic dyes. The aptamers are genetically encodable, and the dyes are cell-permeable and non-toxic. Fluorescence occurs only when a dye binds to its cognate aptamer and forms a light-up aptamer-dye complex—delivering bright, specific RNA signals with minimal background.
Spinach™ includes a variety of aptamer–dye combinations that enables custom color selection and multiplexing. Whether in live cells or fixed samples, Spinach™ makes it easy to monitor RNA expression, localization, and dynamics—fast and in real-time
Just tag your RNA of interest, and see exactly when, where, and how it functions.